Prana Pets Lignans & Melatonin with Biotin for Cushing’s Disease Support for Dogs is designed to help manage your furbaby’s Cushing’s disease symptoms, like excessive thirst and urination. Flaxseed lignans and melatonin work together to help lower excessive cortisol levels and maintain a healthy hormonal balance. Biotin helps with hot spots and other skin irritations, hair loss, and brittle nails. By supplementing melatonin, a natural hormone produced by your dog’s body, you may improve your pup’s sleep quality, which can support their overall wellbeing. Each tablet is perfectly balanced for small dogs weighing up to 25 pounds for easy feeding.