Gentamicin, a broad-spectrum antibiotic, is a highly effective topical treatment for bacterial infections of the skin. Gentamicin is bactericidal against a wide variety of gram-positive and gram-negative bacteria isolated from domestic animals. Betamethasone valerate in veterinary medicine has been shown to provide antiinflammatory and antipruritic activity in the topical management of corticosteroidresponsive infected superficial lesions in dogs.